392224 Software tools in Bioinformatics (S) (WiSe 2019/2020)

In this seminar, students will choose, study and present one of the recent bioinformatic software tools published in peer-reviewed journals. The students are encouraged to suggest topics and tools of their interest or choose one of the following topics (shortlists of tools and a review article for topics will be provided):

• Biclustering

• Read Alignment

• SNP Calling

• Gene Expression Quantification

• Gene Prioritization

• Untargeted Metabolomics

• Metabolite quantification and identification

• Peak alignment of metabolomics data

• Metabolomics data pre-treatment(Scaling, transformation, and normalization)

The participants will give oral presentations (20-45 min’s, optimally about 25 min's) and prepare short summaries (ca. 8 pages) based on original research papers. In their reports, students must (i) briefly explain the problem solved by a selected tool (ii) describe the algorithm(s) implemented in this tool (iii) explain the choice of the tool among its analogs. At the end of the course, the students will peer-review their essays and revise them based on the received feedback.

Requirements for participation, required level

Requirements for participation and required level

Algorithmen und Datenstrukturen I und II oder Grundlagen der Programmierung oder Einführung in die Informatik I und II.