392018 Phylogenetics (V) (WiSe 2016/2017)
Contents, comment
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Die Rekonstruktion von phylogenetischen Bäumen ist eines der ältesten Arbeitsgebiete der Bioinformatik. In dieser Vorlesung werden mit klar algorithmischem Schwerpunkt traditionelle und neuere Verfahren zur Rekonstruktion von phylogentischen Bäumen behandelt. Themen werden u.a. sein:
- Diskussion der mathematischen und biologischen Grundbegriffe
- Formalisierungen des Baumrekonstruktionsproblems
- Merkmals- und distanzbasierte Rekonstruktionsalgorithmen
- Statistische Modellierung von Evolution und Maximum-Likelihood-Baumrekonstruktion
- Bewertung der Qualität von rekonstruierten Bäumen
Bibliography
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- J. Felsenstein. Inferring Phylogenies. Sinauer, 2004.
- R. D. M. Page, E. C. Holmes. Molecular Evolution: A Phylogenetic Approach. Blackwell, 1998.
- D. Graur, W.-H. Li. Fundamentals of Molecular Evolution. Sinauer, 2000.
- D. M. Hillis, C. Moritz, B. K. Mable. Molecular Systematics. Sinauer, 1996.
- M.A. Steel and C. Semple. Phylogenetics. Oxford University Press, 2003.
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| 39-Inf-AB Algorithmen der Bioinformatik | Ausgewählte Vorlesung zu Algorithmen der Bioinformatik | Ungraded examination
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