391001 Biophysikalische Methoden und Modellierung zellulärer Prozesse (V+S) (SoSe 2025)
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Die Vorlesung zu diesem Modul gliedert sich in zwei Teile: Prof. Dr. Merkle stellt die Modellierung zellulärer Prozesse vor und Prof. Dr. Kristian Müller biophysikalische Techniken zur Detektion zellulärer Vorgänge sowie zur Charakterisierung von Proteinen.
Die biophysikalischen Methoden umfassen optische Spektroskopie (UV/VIS, CD, Fluoreszenz, Fluoreszenzpolarisation, DSF) zur Charakterisierung isolierter Proteine, Spektroskopie an Oberflächen (SPR, BLI) zur Charakterisierung von Proteininteraktionen, Durchflusszytometrie zur Charakterisierung zellulärer Prozesse, Mikroskopie (Fluoreszenzmikroskopie, Superresolution, AFM) zur Charakterisierung einzelner Proteine und zellulärer Prozessen sowie Kalorimetrie (DSC, ITC) zur Charakterisierung von Proteinen und Interaktionen. Hierbei werden auch quantitative Aspekte der mikroskopischen Bildverarbeitung und Proteindenaturierung behandelt.
Im Seminar präsentieren die Teilnehmer ausgewählte Aspekte biophysikalischer Methoden oder Modellierungen anhand der Literatur und diskutieren Hintergrund, Anwendung, Aussage und Limitierung der Technik.
Teaching staff
Dates ( Calendar view )
| Frequency | Weekday | Time | Format / Place | Period | |
|---|---|---|---|---|---|
| weekly | Mi | 14-16 | X-E0-215 | 07.04.-18.07.2025 | |
| weekly | Do | 14-16 | U2-232 | 07.04.-18.07.2025
not on: 5/1/25 |
Subject assignments
| Module | Course | Requirements | |
|---|---|---|---|
| 39-M-MBT10T Zelluläre Signalverschaltung und biophysikalische Methoden | Zelluläre Signalverschaltung und biophysikalische Methoden | Study requirement
|
Student information |
| - | Graded examination | Student information |
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| Degree programme/academic programme | Validity | Variant | Subdivision | Status | Semester | LP | |
|---|---|---|---|---|---|---|---|
| Studieren ab 50 |
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