392189 Algorithms in Comparative Genomics (V) (WiSe 2021/2022)
Contents, comment
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Many questions in molecular biology, phylogenetics, and biomedicine can be approached through comparison of two or more genomes. However, a global alignment of multiple large genomes is often infeasible or comes at great expense. It is more efficient to compare genomes on a higher level of abstraction, as given by the succession of single-copy genes or other kinds of unique genomic markers on the chromosomal sequences.
In this course, various models of higher level genome comparison are discussed. We start with the classical breakpoint distance, followed by other simple measures such as SCJ and DCJ. The reversal distance will be discussed, and a general genome rearrangement distance. We will also study methods for the reconstruction of ancestral genomes.
Algorithms discussed in this course are mostly combinatorial by nature, similar to the sequence analysis course.
This course is taught in English.
Requirements for participation, required level
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Required: Algorithms and Data Structures (or comparable)
Recommended: Sequence Analysis and Foundations of Genome Research
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Teaching staff
Dates ( Calendar view )
| Frequency | Weekday | Time | Format / Place | Period |
|---|
Subject assignments
| Module | Course | Requirements | |
|---|---|---|---|
| 39-Inf-SAB_a Spezielle Algorithmen der Bioinformatik | Ausgewählte Vorlesung zu Spezielle Algorithmen der Bioinformatik | Ungraded examination
Graded examination |
Student information |
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- Last update basic details/teaching staff:
- Saturday, October 9, 2021
- Last update times:
- Wednesday, December 22, 2021
- Last update rooms:
- Wednesday, December 22, 2021
- Type(s) / SWS (hours per week per semester)
- V / 2
- Language
- This lecture is taught in english
- Department
- Faculty of Technology
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