391023 Zellkulturtechnik (BPr) (SoSe 2023)
Contents, comment
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Dieses Modul vermittelt praktische Kenntnisse, die zur Benutzung von Säugerzellkulturen zur Produktion von pharmakologisch bedeutsamen Wirkstoffen notwendig sind. Gegenstand des Praktikums ist die Planung, Modellierung, Optimierung und experimentellen Durchführung einer FedBatch-Kultivierung rekombinanter tierischer Zellen in Rührkesselbioreaktoren zur Produktion eines Glykoproteins. In der Auswertung sollen u.a. die Unterschiede zwischen dem vom Modell vorhergesagten und dem realen Prozessverhalten erarbeitet werden.
Ausgangspunkt der Modellierung und Optimierung des FedBatch-Prozesses sind reale Fermentationsdaten der im Praktikum verwendeten Zelllinie. Dabei kommt das Simulationsprogramm 'Berkeley Madonna' zum Einsatz.In einem weiteren Experiment lernen die Teilnehmerinnen und Teilnehmer den inclined-settler als Zellrückhaltemethode für kontinuierliche Perfusionskulturen kennen und erarbeiten den Einfluss der wichtigsten Betriebsparameter.
Teaching staff
Dates ( Calendar view )
| Frequency | Weekday | Time | Format / Place | Period |
|---|
Subject assignments
| Module | Course | Requirements | |
|---|---|---|---|
| 39-M-MBT11P Spezialisierung Zellkulturtechnik Praktikum | Praktikum Zellkulturtechnik | Ungraded examination
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Student information |
The binding module descriptions contain further information, including specifications on the "types of assignments" students need to complete. In cases where a module description mentions more than one kind of assignment, the respective member of the teaching staff will decide which task(s) they assign the students.
E-Learning Space
A corresponding course offer for this course already exists in the e-learning system. Teaching staff can store materials relating to teaching courses there:
- Registered number: 7
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- Address:
- SS2023_391023@ekvv.uni-bielefeld.de
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- Coverage:
- 7 Students to be reached directly via email
- Notes:
- Additional notes on the electronic mailing lists
- Email archive
- Number of entries 1
- Open email archive
- Last update basic details/teaching staff:
- Wednesday, November 23, 2022
- Last update times:
- Monday, June 26, 2023
- Last update rooms:
- Monday, June 26, 2023
- Type(s) / SWS (hours per week per semester)
- BPr /
- Department
- Faculty of Technology
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