Every winter semester
10 Credit points
For information on the duration of the modul, refer to the courses of study in which the module is used.
Practical Course
The students gain in-depth insights into current research topics and experimental methods in organic chemistry, focusing on sustainable synthesis strategies. They are able to plan and carry out complex, multi-step syntheses while considering temporal and safety aspects as well as sustainability issues. Additionally, they are capable of isolating and purifying the synthesized products and analyzing their structure using spectroscopic methods (NMR, MS, IR, UV). They acquire the ability to write a scientific report in the style of contemporary academic publications and gain experience in presenting scientific content. The students are able to recognize synthesis strategies, evaluate them including aspects of sustainability, and apply them in the laboratory.
Lecture
After the lecture, students will have in-depth knowledge of stereochemistry. They are familiar with the nomenclature of chiral compounds and know analytical methods for chiral compounds. They will be able to recognise the symmetry properties of molecules and describe stereochemical processes and apply stereoselective synthesis methods on this basis. They are familiar with the most important strategies for synthesising chiral compounds.
Students are familiar with pericyclic reactions and understand the reaction mechanism based on the boundary orbitals involved and the preservation of orbital symmetry. They can classify pericyclic reactions and predict reactivity as well as stereoselectivity and regioselectivity for simple examples. In addition, students have knowledge of reactive intermediates (carbenes, nitrenes, arynes) and the associated reaction mechanisms.
Practical Course
Topics include organic syntheses with main group metal organyls and transition metal-catalysed cross-coupling reactions, stereoselective syntheses and enzyme-catalysed organic transformations. A further focus is on spectroscopy (NMR, MS) for reaction control and structure elucidation. Preparations are selected specifically in order to expand the range of experimental methods, to deepen expertise in the application of spectroscopic techniques for analysing chemical processes and to learn more sustainable synthesis methods.
Lecture
Stereochemistry and stereoselective synthesis: stereoisomers, CIP system, conformations, diastereomers, analysis of chiral compounds, substrate-, auxiliary- and reagent-induced stereoselectivity, double asymmetric induction, chirality transfer, thermodynamic vs. kinetic control, examples of enantiodifferentiating reactions, enantiofacial differentiation, enantiomeric differentiation, enantiotopic differentiation, diastereodifferentiating reactions.
Pericyclic reactions: Properties and types of pericyclic reactions, cycloaddition, frontier orbital approach, theoretical principles, conservation of orbital symmetry, reactivity, stereospecificity, diastereo- and regioselectivity, electrocyclic reactions, sigmatropic rearrangement, group transfer reactions, reactive intermediates: carbenes, nitrenes, arynes.
For the lecture:
Advanced modules in inorganic, organic and physical chemistry
For the practical course:
21-M13,
21-M12,
21-M21
In order to do justice to both the theoretical and practical parts of the module, an oral examination is required to evaluate the theoretical knowledge of the entire module, as well as a portfolio of various experiments to ensure the successful teaching of practical laboratory skills.
Module structure: 1 SL, 1 bPr, 1 uPr 1
| Allocated examiner | Workload | LP2 |
|---|---|---|
|
Teaching staff of the course
Organic Chemistry - Specialisation: Focus Sustainablity
(internship with seminar component / laboratory internship with seminar component)
Seminar talk, about 20 minutes. |
see above |
see above
|
The portfolio of scientific experiments comprises 6-7 experiments, the elements of which are examined during the course. The examination components of an experiment are basically the following four elements, which are completed one after the other:
1. review of prior knowledge including safety-relevant aspects
2. carrying out the experiment and recording the execution, observations and results
3. preparation of a written experiment protocol or an oral presentation of the results
4. discussion of the experimental protocol, the results and the theory of the experiment (final examination)
Subsequent elements of the experiment can only be started if the previous elements have been passed. In the case of individual experiments, individual elements may be omitted or, in relation to point 2, replaced by theorised elements after appropriate notification, provided that the learning objectives associated with the experiment are thereby achieved. An attempt is passed if all four elements have been completed and fulfil the requirements despite existing deficiencies.
If an element of an attempt is not passed, there are two options:
a) The entire attempt can be repeated or
b) individual elements can be repeated if elements have already been assessed as "passed" and individual learning objectives of the attempt have therefore been achieved.
This is decided by the person authorised to conduct the examination.
The attempt or individual elements of an attempt can be repeated a maximum of once in this way. A total of one attempt per practical course and portfolio can be repeated in the aforementioned sense.
40 - 45 minutes.
| Degree programme | Version | Recommended start 3 | Duration | Mandatory option 4 |
|---|---|---|---|---|
| Sustainable Chemistry / Bachelor of Science [FsB vom 05.03.2026] | Bachelor with One Core Subject (Academic) | 5. | 2 semesters | Obligation |
The system can perform an automatic check for completeness for this module.
Sustainable Chemistry / Bachelor of Science: Bachelor with One Core Subject (Academic)