The biological clock of plants
‘research_tv’ presents Bielefeld research on Nobel Prize topic
On Sunday (10.12.2017), the Americans Jeffrey C. Hall, Michael Rosbash, and Michael W. Young were awarded the Nobel Prize for Medicine and Physiology for their research on the biological clock. They discovered the molecular mechanisms controlling biological rhythms. A new ‘research_tv’ report describes how scientists at Bielefeld are also advancing research on the biological clock. The biochemist Professor Dr. Dorothee Staiger from Bielefeld University explains what the three Nobel Prize winners have achieved and reports on the discoveries her research team has made together with collaborators.
Whereas the American colleagues have been analysing the biological clock in animals, Staiger’s ‘RNA Biology and Molecular Physiology’ research group has been studying biological rhythms in plants. ‘At the time when Hall, Rosbash, and Young were discovering the first clock protein, we discovered another protein in plants that works in a similar way,’ reports Staiger. ‘The difference is that it does not work completely independently; it depends on the central biological clock. Hence, we have called it an auxiliary clock. This was the first auxiliary clock to be identified on the molecular level.’
Martin Lewinski from Staiger’s research group together with Professor Dr. Ivo Große’s team at the Institute of Computer Science of the Martin Luther University Halle-Wittenberg then used bioinformatics procedures to determine how this auxiliary clock protein and these messenger RNAs interact. Afterwards, Staiger’s team studied how the auxiliary clock regulates these messenger RNAs by extracting messenger RNAs from the plants and analysing them every two hours over a period of several days.
‘Binding the auxiliary clock protein to the messenger RNAs is important, because it helps to keep the biological clock running,’ says Staiger.
• research_tv-report: 'Die innere Uhr der Pflanzen’: https://youtu.be/_Ls4Z2YZ6Og
• ‘Biological Timing: Biologists Investigate the Mechanism of an Auxiliary Clock’ (press release from 17.11.2017): http://bit.ly/2j7ObI6
• Research article on the clock-regulated protein AtGRP7: http://bit.ly/2AGIuvP
• Overview of research_tv science videos: http://bit.ly/2Ahc2Mx
Prof. Dr. Dorothee Staiger, Bielefeld University
Faculty of Biology
Telephone: +49 521 106-5609