Published on 29. Mai 2020
Fibre laser microscopy to be used in clinical applications
When investigating how tumors grow, or how pharmaceuticals affect different types of cells, researchers have to understand how molecules within a cell react – and interact. This is possible with modern laser microscopy. Until now, however, molecules in cell specimens had to be labelled with fluorescent substances in order to make them visible, and this can distort the very behavior of the molecules. Research groups from Bielefeld University and the University of Hong Kong have developed a laser microscope that works without having to label the molecules. For this, the researchers innovated a unique compact fibre laser instead of the solid-state lasers that had previously been used. The new microscope generates far less noise when in use than customary designs, making it suitable for use in operating rooms. The researchers presented their innovative technology in the journal ‘Light: Science and Applications,’ which is published by Springer Nature.