Frau Dr. Martina Viefhues

Professional experience and projects

• since 10/2018 Equal opportunity commissioner physics faculty, Bielefeld university

• since 12/2015 Group leader Micro- and nanofluidic, Bielefeld University, Department of Physics, Experimental Biophysics and applied Nanosciences: Micro- and Nanofluidics and Nanomembranes

• 06/2015-11/2015 R&D Scientist, Micronit Microfluidics, Enschede, The Netherlands

• 04/2015 Visiting Scientist, TU Graz, (Nidetzky group): Characterization of surface immobilized enzymes

• 12/2013-05/2015 Marie Curie Fellow, Industrial Post-Doc, Micronit Microfluidics, Enschede, The Netherlands: EuroMBR, Microbioreactors for biocatalytic applications

• 05/2011-03/2013 Co-group leader Micro- and nanofluidics, Bielefeld University, Department of Physics, Experimental Biophysics and applied Nanosciences: Dielectrophoresis based analysis and preparation

Academic education

• 12/2012 Dissertation Physics, Bielefeld University (Prof. Dario Anselmetti): Analysis and Preparation of (Bio)Nanoobjects in Nano-Microfluidic Devices

• 05/2009 M.Sc. Biophysics, Bielefeld University (Dr. Jan Regtmeier): Continuous separation of DNA and DNA-complexes in microfluidic systems

• 08/2007 B.Sc. Physics, Bielefeld University (Prof. Alexandra Ros): Static and dynamic surface coatings in Poly(dimethylsiloxane) and quartz microfluidic channels

Research fields

Micro- and nanofluidics: Electrokinetic migration phenomena; New analysis and manipulation methods for biomolecules and whole cell; Microfluidic tools for studying protoplast fusion and reorganisation

Nanomembranes: Fabrication and characterization of solid state and lipid membranes; Controlled translocation of biopolymers through nanopores

Selected publications

• V. Ortseifen, M. Viefhues, L. Wobbe, and A. Grünberger, Microfluidics for Biotechnology: Bridging Gaps to Foster Microfluidic Applications, Fontiers, 2020

• M.S. Epping, S. Wedde, A. Grundmann, M. Radukic, H. Gröger, A. Hummel, and M. Viefhues, Dielectrophoretic analysis of the impact of isopropyl alcohol on the electric polarisability of Escherichia coli whole-cells, Anal. Bioanal. Chem. 2020.

• D. Gilzer, R. Hillmann, Lukas-Goett-Zink, Jessica L. Klocke, M. Viefhues, D. Anselmetti, and T. Kottke, Biphasic Formation of 2D Nanomembranes by Photopolymerization of Diacetylene Lipids as Revealed by Infrared Difference Spectroscopy, Langmuir, 2019

• R. Hillmann, M. Viefhues, L. Goett-Zink, D. Gilzer, Th. Hellweg, A. Gölzhäuser, T. Kottke, and D. Anselmetti, Characterization of Robust and Free-Standing 2D-Nanomembranes of UV-Polymerized Diacetylene Lipids, Langmuir, 2018

• D. Valikhani, J.M. Bolivar, M. Viefhues, D.N. McIlroy, E.X. Vrouwe, and B. Nidetzky, A spring in performance: silica nanosprings boost enzyme immobilization in microfluidic channels, ACS Applied Materials & Interfaces, 2017.

• M. Viefhues, S. Sun, D. Valikhani, B. Nidetzky, E.X. Vrouwe, T. Mayr, and J.M. Bolivar Bolivar, Tailor-made resealable micro(bio)reactors providing easy integration of in-situ sensors, JMM, 2017.

• M. Viefhues and R. Eichhorn, DNA dielectrophoresis: theory and applications a review, Electrophoresis (special issue), 2017, invited article.

• S. Knust, D. Kreft, R. Hillmann, A. Meyer, M. Viefhues, P. Reimann, and D. Anselmetti, Measuring DNA Translocation Forces Through MoS2 -Nanopores with Optical Tweezers, Materials Today: Proceedings, 2016

• M. Viefhues, S. Wegener, A. Rischmüller, M. Schleef, and D. Anselmetti, Dielectrophoresis based continuous flow nano sorter: fast quality control of gene vaccines. Lab Chip (special issue), 2013.

• M. Viefhues, R. Eichhorn, E. Fredrich, J. Regtmeier, and D. Anselmetti, Continuous and reversible mixing or demixing of nanoparticles by dielectrophoresis. Lab Chip, 2012, invited article.

Selected talks

• M. Viefhues, New electrokinetic analytical methods for whole-cell biocatalyst studies, EuroMBR international training course, Braunschweig, Germany, 2019 (invited talk)

• M. Viefhues, New electrokinetic analytical methods for whole-cell biocatalyst studies, EuroMBR international training course, Braunschweig, Germany, 2018 (invited talk)

• M. Viefhues, Microfluidic devices: fabrication and applications with enzymes and biomolecules, Colloquium talk at Siegen University, Faculty of physical and theoretical chemistry, Siegen, Germany, 2016, (invited talk).

• M. Viefhues, D. Valikhani, S. Sun, T. Mayr, E. Vrouwe, M. Blom, B. Nidetzky, and J. Bolivar Bolivar, Resealable flowcells with integrated oxygen sensing layers for enzymatic reaction studies, MNE2015, The Hague, The Netherlands, 2015.

• M. Viefhues, E. Vrouwe, and M. Blom, Resealable flowcells for microbioreactors, SAMOSS international summer school, Madrid, Spain, 2014, (invited talk).

• M. Everwand, D. Anselmetti, and J. Regtmeier, Continuous separation of DNA protein complexes in hybrid micro-nanofluidic devices, 4th Lab-on-a-Chip European Congress, Dublin, Ireland, 2010.

• M. Everwand, D. Anselmetti, and J. Regtmeier, On-chip continuous-flow interaction studies of DNA and protein complexed DNA, 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS2010), Groningen, The Netherlands, 2010.